The Right Opioid Dosing And Avoiding The Addiction Trap
by Kevin Graham
The miracle of opioid pain relief is fatally limited by tolerance, addiction, and respiratory depression. Buprenorphine, when combined with a mu agonist, results in game-changing effects. Patients experience potent, dose-related analgesia from the agonist, but have NO euphoria. The therapeutic window is widened. Patients unable to control their use of a mu agonist alone gain that control when on buprenorphine. And most exciting, buprenorphine indefinitely anchors tolerance, maintaining analgesia WITHOUT DOSE ESCALATION. This finding offers huge implications for pain management and <a href="http://525md.com">opioid dosing</a>.
Opioid receptors are present in everyone's body. These receptors are responsible for bringing emotions like pleasure and pain in the body. Several narcotics, such as hydrocodone and oxycontin, give relief while one is experiencing severe pain. The main problem with the opioid is they are very addictive in nature and can result in death if taken in high dose. There has been a huge usage of the narcotic medication by people of every age group in the United States.
Is it possible for chronic opioid therapy to make patients worse? The answer is yes, and it is termed opioid-induced hyperalgesia (OIH). It is a paradoxical condition whereby patients become oversensitive to acute pain. There is a scarcity of literature on the subject of how often it occurs, what presents risk factors for its occurrence, and whether or not there is a dosing relationship for narcotics towards developing OIH.
Research shows narcotic use is higher among the less educated and unemployed. A recent report in the American Journal of Medicine specifically looked at fibromyalgia patients receiving opioids for their pain. There was an increased incidence of unemployment, disability payments, and history of substance abuse. Also, the statistics showed overall lower education and an increased incidence of unstable psychiatric disorders. The study was not small and contained over 450 patients, so the results were most likely valid despite potential statistical variances.
Methadone is a synthetic opioid mainly prescribed as a long range replacement therapy for dependence to opioids. While methadone was once administered strictly at licensed methadone rehabilitation detox hospitals and drug clinics, within the past several years the drug is being prescribed in a pill form for severe pain. As such, the drug now can be discovered on the street, and quickly has become a top cause of accidental overdose within recreational drug users.
Opioid-induced hyperalgesia is a condition that can result from long-term opioid use. It represents a heightened perception of pain and can make one feel worse with more pain sensation. The solution to this problem is a decrease or discontinuation of the medication which should be accomplished under medical supervision. The discontinuation can result in less pain than while on the medications.
Sleep is affected significantly by opioids. A large review of studies was published in Postgraduate Medicine looking at the effect of narcotics on sleeping patterns. What popped out? Well, opiate users displayed significant incidence of insomnia, arousals, and wakefulness.
Seeking help from a clinic, a private doctor, or an addiction-breaking support group is safer options for quitting. Support group members have been there themselves and understand what it is like to leave behind an addiction. Medical professionals can help addicts leave the drugs behind on a gradual basis so that their bodily systems are not compromised.
The objective in utilizing opioid replacement therapy includes removing the uncomfortable day-to-day withdrawal which interferes with an individual's capability of normally functioning. The level of opiate withdrawal sickness differs from one person to another as does the severity of each individual's addiction.
When you are looking for the facts about <a href="http://525md.com">opioid dosing</a>, come to the web pages online today. More details are available at http://525md.com now.
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New Unique Article!
Title: The Right Opioid Dosing And Avoiding The Addiction Trap
Author: Kevin Graham
Email: nathanwebster335@live.com
Keywords: opioid dosing
Word Count: 590
Category: Medicine
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